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IR VIVO™ Preclinal Imager

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IR VIVO™ Preclinal Imager

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IR VIVO™ Preclinical Imaging System opens a new window on living bodies

Using the first (NIR) and second biological window (NIR-II) from 900-1620 nm, Photon etc.’s IR VIVO™ preclinical imager provides multispectral or hyperspectral infrared imaging capabilities for in vivo studies on small animals or living organisms. It combines micron-scale spatial resolution, real-time imaging and full spectral coverage throughout small animals. Emission of several fluorophores can be isolated with a high-efficiency tunable filter and ultra-low noise scientific-grade InGaAs camera.

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Product Description

IR VIVO™ Preclinical Imaging System opens a new window on living bodies

Using the first (NIR) and second biological window (NIR-II) from 900-1620 nm, Photon etc.’s IR VIVO™ preclinical imager provides multispectral or hyperspectral infrared imaging capabilities for in vivo studies on small animals or living organisms. It combines micron-scale spatial resolution, real-time imaging and full spectral coverage throughout small animals. Emission of several fluorophores can be isolated with a high-efficiency tunable filter and ultra-low noise scientific-grade InGaAs camera.

Allows seeing both structure and function by combining:

  • Fast acquisition speed
  • Micron-scale spatial resolution
  • Centimeter-scale penetration depth
  • Multicolour imaging

IR VIVO™

EMISSION SPECTRAL RANGE850 - 1620 nm
FILTER TYPESMultispectral: Filter wheel
Hyperspectral: HyperCube™
HYPERCUBE SPECTRAL RESOLUTION< 4 nm
ILLUMINATION SOURCE730, 780, 808 or 810 nm LEDs
Other sources available upon request
ILLUMINATION AREA15.6 x 12.5 cm field of view for 3 mice model
FIELD OF VIEWVariable from 5 x 4 cm to 15.6 x 12.5 cm
OVERALL INSTRUMENT DIMENSIONSTabletop
About 75 x 115 x 75 cm
STAGE TEMPERATUREUp to 40ºC
ANESTHETIC TUBING AND NOSECONE3-mice anesthetic gas manifold supplied
COMPUTERPC with Windows 7-64 bits included
IMAGING SOFTWAREPHySpec™ software
SPECTRAL DATA FORMATHDF5, FITS
SINGLE IMAGE DATA FORMATHDF5, CSV, JPG, PNG, TIFF
POWER REQUIREMENT120 VAC / 12 A / 60 Hz
ACQUISITION MODE AVAILABLEUnfiltered (Broadband)
VIDEO MODEMegapixel camera for sample visualization

CAMERA

TYPEInGaAs (ZephIR™ 1.7)
FPA640 × 512 pixels
PIXEL SIZE15µm
QE< 75%
DYNAMIC RANGE13/15 bits

Photon etc.’s IR VIVO system

Video of IR VIVO imaging experiment showing the biodistribution and pharmacokinetics of ICG in real-time. IR VIVO is able to visualize basic NIR probes at high resolutions allowing to address questions in biology in ways not yet imagined. From one single injection, it was possible to obtain measurements of heartbeat, respiration and intestinal contraction rates.

Photon etc.’s Global Imaging Technology

This video shows the conceptual difference between hyperspectral global imaging and raster scan (line-scan, push- broom). With global imaging, the gain in acquiring 3D data, 2D spatial and 1D spectral, is important since only a few monochromatic images are required to cover the complete spectral range where one needs to take the full spectrum for each point or line in the image with other technologies.

Download Spec Sheet