VISQUE® InVivo Smart-LF

VISQUE™ InVivo Smart-LF is an ideal in vivo imaging system for bioluminescent and fluorescent imaging
as it provides outstanding performance at a reasonable price. The scientific CMOS camera developed
solely for VISQUE™ InVivo Smart-LF provides high sensitivity with a quantum efficiency up to 94% at
550 ㎚. Its high sensitivity and low noise capabilities allow you to precisely detect and quantitate very
weak signals in bioluminescent and fluorescent imaging. For multispectral fluorescent imaging, the
system is equipped with a filter wheel providing four filter slots for GFP, PE, Cy5.5 and ICG fluorescent
dyes and five filter slots for customized filters. For precise pharmacokinetic analysis and biodistribution
studies, VISQUE™ InVivo Smart-LF not only allows real-time imaging of up to 37 frames per second but
also provides 10 patented algorithms to analyze kinetics of drug distribution.
VISQUE™ InVivo Smart-LF featuring a compact size also allows you to save valuable laboratory space
and to simply operate it with a laptop computer.

Categories: Preclinical / In-Vivo Imaging, Vieworks

Description
Additional information

Description

Main Features:

Highly sensitive imaging from 300-940 nm
Intelligent image analysis software
Real-time imaging
Space-Saving compact design
Reasonable price with outstanding performance

Applications:

Pharmacology and toxicology
Oncology
Cardiovascular function
Photo-stability test of molecules
Cell Therapy tests
Biodistribution of nanoparticles

Fast and Convenient Analysis Tools:

One-click analysis
- Automatic display fluorescence level and simple setting
Image Processing
- Autofluorescence signal removal, merge of multi-spectral images.
Report Mode
- The acquisition setup information, raw image, ROI, the range of pseudocolor bar, comments, etc.

Additional information

Details	High-sensitivity Bioluminescent & Fluorescent Imaging Scientific CMOS Camera with Cooling Technology Optimized solution for high-end scientific applications Min. image pixel size: 26.5 µm Cooling: -50℃ below ambient temperature High-sensitivity sCMOS Image Sensor Quantum efficiency: Max. 94% @ 550 nm >85% 450 – 700 nm >30% 300 – 950 nm Readout noise: 1.6e- Fast-speed Imaging Acquisition Uniformed-quality image with high-speed image acquisition up to 37 frames per second
Literature	In Vivo Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe Link: https://pubs.acs.org/doi/10.1021/acs.analchem.0c02670 Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy Link: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00882 Biodegradable Mesoporous Silica Achieved via Carbon Nanodots-Incorporated Framework Swelling for Debris-Mediated Photothermal Synergistic Immunotherapy Link: https://pubs.acs.org/doi/10.1021/acs.nanolett.9b02448 Penta-fluorophenol: A Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma. Link: https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc01085e#!divAbstract Osteogenesis and angiogenesis are simultaneously enhanced in BMP2-/VEGF-transfected adipose stem cells through activation of the YAP/TAZ signaling pathway. Link: https://pubs.rsc.org/en/content/articlelanding/2019/BM/C9BM01037H#!divAbstract Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance. Link: https://genome.cshlp.org/content/29/9/1442 Conjugation of prostate cancer-specific aptamers to polyethylene glycol-grafted polyethylenimine for enhanced gene delivery to prostate cancer cells. Link: https://www.sciencedirect.com/science/article/pii/S1226086X18305331?viaihub A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy. Link: https://www.sciencedirect.com/science/article/pii/S1742706119304258?viaihub Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis Link: https://www.sciencedirect.com/science/article/pii/S0006291X15304708?viaihub

Details

High-sensitivity Bioluminescent & Fluorescent Imaging
Scientific CMOS Camera with Cooling Technology

Optimized solution for high-end scientific applications
Min. image pixel size: 26.5 µm
Cooling: -50℃ below ambient temperature
High-sensitivity sCMOS Image Sensor

Quantum efficiency: Max. 94% @ 550 nm
>85% 450 – 700 nm
>30% 300 – 950 nm
Readout noise: 1.6e-
Fast-speed Imaging Acquisition

Uniformed-quality image with high-speed image
acquisition up to 37 frames per second

Literature

In Vivo Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe
Link: https://pubs.acs.org/doi/10.1021/acs.analchem.0c02670

Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy
Link: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00882

Biodegradable Mesoporous Silica Achieved via Carbon Nanodots-Incorporated Framework Swelling for Debris-Mediated Photothermal Synergistic Immunotherapy
Link: https://pubs.acs.org/doi/10.1021/acs.nanolett.9b02448

Penta-fluorophenol: A Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma.
Link: https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc01085e#!divAbstract

Osteogenesis and angiogenesis are simultaneously enhanced in BMP2-/VEGF-transfected adipose stem cells through activation of the YAP/TAZ signaling pathway.
Link: https://pubs.rsc.org/en/content/articlelanding/2019/BM/C9BM01037H#!divAbstract

Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance.
Link: https://genome.cshlp.org/content/29/9/1442

Conjugation of prostate cancer-specific aptamers to polyethylene glycol-grafted polyethylenimine for enhanced gene delivery to prostate cancer cells.
Link: https://www.sciencedirect.com/science/article/pii/S1226086X18305331?viaihub

A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy.
Link: https://www.sciencedirect.com/science/article/pii/S1742706119304258?viaihub

Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis
Link: https://www.sciencedirect.com/science/article/pii/S0006291X15304708?viaihub

VISQUE® InVivo Smart-LF

VISQUE® InVivo Smart-LF

Description

Additional information

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