VISQUE® InVivo Smart

Description

Main Features:

Optimized solution for high-end scientific applications
Min. image pixel size: 20 ㎛ (@7.5x)
Quantum Efficiency: 72% at 595 nm
Dynamic Range: 87 dB
Dark Current: < 10 e-/s/pix @ 30℃
Uniformed-quality image with high-speed image acquisition up to 30 frames per second

Applications:

Imaging solid tumors & tracking metastatic tumors
Assessment of cardiovascular and/or Lymphatic structure and functions
Evaluating the therapeutic efficacy of new drugs against cancer, arthritis, atherosclerosis, autoimmune disorders or angiogenesis etc.
Analysis of the pharmacokinetics of new drugs.

0 hr: immediately after IP injection of the exosome-ICG complex.
The blue arrow indications the injection spot.

Additional information

Details	Fast and Convenient Tools: Once-click analysis: automatic display of fluorescence level, ROI analysis units, etc. Image Process: autofluorescence signal removal, merge of multi-spectral images Report Mode: shows the acquisition setup information, Raw image, ROI, the range of Pseudocolor bar, comments, etc. Convenient Post-Image Analysis Edition Tools: *.cif analysis file output The display and analysis of four-different images in one screen. Also supports tif, bmp, jpg, png Supports time-lapse imaging and analysis software
Literature	In Vivo Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe Link: https://pubs.acs.org/doi/10.1021/acs.analchem.0c02670 Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy Link: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00882 Detecting Cysteine in Bioimaging with a Near‐Infrared Probe Based on a Novel Fluorescence Quenching Mechanism Link: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.202000313 Biodegradable Mesoporous Silica Achieved via Carbon Nanodots-Incorporated Framework Swelling for Debris-Mediated Photothermal Synergistic Immunotherapy. Link: https://pubs.acs.org/doi/10.1021/acs.nanolett.9b02448 Osteogenesis and angiogenesis are simultaneously enhanced in BMP2-/VEGF-transfected adipose stem cells through activation of the YAP/TAZ signaling pathway. Link: https://pubs.rsc.org/en/content/articlelanding/2019/BM/C9BM01037H#!divAbstract Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance. Link: https://genome.cshlp.org/content/29/9/1442 Conjugation of prostate cancer-specific aptamers to polyethylene glycol-grafted polyethylenimine for enhanced gene delivery to prostate cancer cells. Link: https://www.sciencedirect.com/science/article/pii/S1226086X18305331?viaihub Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis Link: https://www.sciencedirect.com/science/article/pii/S0006291X15304708?viaihub Age-related changes in pial arterial structure and blood flow in mice: Link: https://www.sciencedirect.com/science/article/pii/S0197458015004650?viaihub Noninvasive Optical Measurement of Cerebral Blood Flow in Mice Using Molecular Dynamics Analysis of Indocyanine Green Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048383 Efficient differentiation of human pluripotent stem cells into functional CD34 progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways. Link: http://www.bloodjournal.org/content/116/25/5762.long?sso-checked=true Unsorted human adipose tissue-derived stem cells promote angiogenesis and myogenesis in murine ischemic hindlimb model. Link: https://www.sciencedirect.com/science/article/abs/pii/S0026286210001275 Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics. Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=-PLoS+One.+20094(1)e4275

Details

Fast and Convenient Tools:

Once-click analysis: automatic display of fluorescence level, ROI analysis units, etc.
Image Process: autofluorescence signal removal, merge of multi-spectral images
Report Mode: shows the acquisition setup information, Raw image, ROI, the range of Pseudocolor bar, comments, etc.

Convenient Post-Image Analysis Edition Tools:

*.cif analysis file output
The display and analysis of four-different images in one screen. Also supports tif, bmp, jpg, png
Supports time-lapse imaging and analysis software

Literature

In Vivo Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe
Link: https://pubs.acs.org/doi/10.1021/acs.analchem.0c02670

Discovery of a Monoiodo Aza-BODIPY Near-Infrared Photosensitizer: in vitro and in vivo Evaluation for Photodynamic Therapy
Link: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00882

Detecting Cysteine in Bioimaging with a Near‐Infrared Probe Based on a Novel Fluorescence Quenching Mechanism
Link: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.202000313

Biodegradable Mesoporous Silica Achieved via Carbon Nanodots-Incorporated Framework Swelling for Debris-Mediated Photothermal Synergistic Immunotherapy.
Link: https://pubs.acs.org/doi/10.1021/acs.nanolett.9b02448

Osteogenesis and angiogenesis are simultaneously enhanced in BMP2-/VEGF-transfected adipose stem cells through activation of the YAP/TAZ signaling pathway.
Link: https://pubs.rsc.org/en/content/articlelanding/2019/BM/C9BM01037H#!divAbstract

Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance.
Link: https://genome.cshlp.org/content/29/9/1442

Conjugation of prostate cancer-specific aptamers to polyethylene glycol-grafted polyethylenimine for enhanced gene delivery to prostate cancer cells.
Link: https://www.sciencedirect.com/science/article/pii/S1226086X18305331?viaihub

Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis
Link: https://www.sciencedirect.com/science/article/pii/S0006291X15304708?viaihub

Age-related changes in pial arterial structure and blood flow in mice:
Link: https://www.sciencedirect.com/science/article/pii/S0197458015004650?viaihub

Noninvasive Optical Measurement of Cerebral Blood Flow in Mice Using Molecular Dynamics Analysis of Indocyanine Green
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048383

Efficient differentiation of human pluripotent stem cells into functional CD34 progenitor cells by combined modulation of the MEK/ERK and BMP4 signaling pathways.
Link: http://www.bloodjournal.org/content/116/25/5762.long?sso-checked=true

Unsorted human adipose tissue-derived stem cells promote angiogenesis and myogenesis in murine ischemic hindlimb model.
Link: https://www.sciencedirect.com/science/article/abs/pii/S0026286210001275

Quantitative Analysis of Peripheral Tissue Perfusion Using Spatiotemporal Molecular Dynamics.
Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=-PLoS+One.+20094(1)e4275

VISQUE® InVivo Smart

Description

Additional information

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